Early CAR-T trial results show promise for stiff person syndrome

Health · First reported 9 Nov, 16:00 · Updated 16:37

Image: Wikimedia Commons · NASA Johnson Space Center · Public domain

Two people with stiff person syndrome reported improvements in everyday function after receiving CAR-T therapy in a small clinical trial. Researchers say larger trials are needed to assess whether the gains will last.

Two trial participants reported improvements in daily functioning after CAR-T therapy, including walking and returning to work.
The study was published in JAMA Neurology, and its researchers say larger trials may follow.
Celine Dion announced her stiff person syndrome diagnosis in December 2022.

Summary written by Lux AI from 2 articles

Key facts

Treatment studied: CAR-T cell therapy
Trial participants described: Two people with stiff person syndrome
Study publication: JAMA Neurology
Dion’s diagnosis announcement: December 2022
Next research step: Larger trials may follow; whether improvements will be sustained remains an open question